The study examines Sweden’s strategy for total defense, emphasizing inter-sectoral collaboration at the regional level. Specifically, it aims to identify potential challenges in such collaboration, leading to the following overarching research question: What are the principal challenges linked to cross-sector collaboration within Sweden’s total defense strategy at the regional level. The study is based on interviews and observations from various collaborative exercises. Six participants from different organizations specializing in total defense collaboration were interviewed. In addition to interviews, six observations were conducted during different collaborative exercises, each resulting in field notes forming the basis for analysis. Data collection took place between August 2022 and October 2023. The analysis of collected data identifies three overarching themes – inability, unwillingness, and lack of synchronization – depicting the challenges of collaboration in total defense. These themes intertwine and construct a complex situation, described as “a colossus on clay feet,” referring to various mechanisms of inertia in civil-military collaboration. The study concludes that the identified themes pose significant theoretical challenges, suggesting inherent vulnerabilities in the concept that may impede its effectiveness, with the most concerning aspect being the inability to address fundamental problems even amidst increased resources and determination, necessitating a focused research direction to tackle these dilemmas.