This chapter examines the concept of mission command in light of ongoing trends in the evolution of warfare and military operations. The chapter starts with a discussion of mission command respectively in terms of a culture or command philosophy, and as a set of methods and practices of command. It then discusses the role and future utility of mission command in light of developments in three broad areas of importance to the evolution of military command. These are, first, general trends in the current and future operational environment with implications for the command of land operations, with a focus on the US Army’s concept of multi-domain operations. The second area is the ever-increasing demands for information management, and the daunting challenge it poses for any military command system. The third is developments in information technology over the last decades and the more recent shift toward artificial intelligence and automation.