This brief discusses the Quad’s agenda and how its design is tailored to the Indo-Pacific. It argues that working with the Quad will entail individual, like-minded European and Indo-Pacific countries coordinating in ad hoc, flexible formats. Such arrangements should focus on niche issues where European countries and the EU have overlapping interests with Quad members, such as Indian Ocean and maritime security or ensuring cheap, high-quality, and reliable technologies to assist developing countries’ transition to renewable energy. It concludes with a set of policy recommendations on how to further this agenda.