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Cancer - An Insurgency of Clones
Lund Univ, Dept Lab Med, Div Clin Genet, Lund, Sweden; Lund Univ, Dept Clin Sci, Div Oncol & Pathol, Lund, Sweden; Skåne Univ & Reg Labs, Dept Pathol, Lund, Sweden..ORCID iD: 0000-0002-0301-426X
Swedish Defence University, Department of Security, Strategy and Leadership (ISSL), ISSL Directorate.ORCID iD: 0000-0002-9580-7995
2017 (English)In: Trends In Cancer, ISSN 2405-8025, Vol. 3, no 2, p. 73-75Article in journal, Editorial material (Other academic) Published
Abstract [en]

Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

Place, publisher, year, edition, pages
2017. Vol. 3, no 2, p. 73-75
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Cancer and Oncology
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URN: urn:nbn:se:fhs:diva-8013DOI: 10.1016/j.trecan.2016.11.010ISI: 000425966800001PubMedID: 28718446OAI: oai:DiVA.org:fhs-8013DiVA, id: diva2:1229045
Available from: 2018-06-29 Created: 2018-06-29 Last updated: 2018-06-29

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Egnell, Robert

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